Of Headless Mice…And Men

Of Headless Mice...And Men
Last year Dolly the cloned sheep was received with wonder, titters and some vague apprehension. Last week the announcement by a Chicago physicist that he is assembling a team to produce the first human clone occasioned yet another wave of Brave New World anxiety. But the scariest news of all–and largely overlooked–comes from two obscure labs, at the University of Texas and at the University of Bath. During the past four years, one group created headless mice; the other, headless tadpoles. For sheer Frankenstein wattage, the purposeful creation of these animal monsters has no equal. Take the mice. Researchers found the gene that tells the embryo to produce the head. They deleted it. They did this in a thousand mice embryos, four of which were born. I use the term loosely. Having no way to breathe, the mice died instantly. Why then create them? The Texas researchers want to learn how genes determine embryo development. But you don’t have to be a genius to see the true utility of manufacturing headless creatures: for their organs–fully formed, perfectly useful, ripe for plundering. Why should you be panicked? Because humans are next. “It would almost certainly be possible to produce human bodies without a forebrain,” Princeton biologist Lee Silver told the London Sunday Times. “These human bodies without any semblance of consciousness would not be considered persons, and thus it would be perfectly legal to keep them ‘alive’ as a future source of organs.” “Alive.” Never have a pair of quotation marks loomed so ominously. Take the mouse-frog technology, apply it to humans, combine it with cloning, and you are become a god: with a single cell taken from, say, your finger, you produce a headless replica of yourself, a mutant twin, arguably lifeless, that becomes your own personal, precisely tissue-matched organ farm. There are, of course, technical hurdles along the way. Suppressing the equivalent “head” gene in man. Incubating tiny infant organs to grow into larger ones that adults could use. And creating artificial wombs , given that it might be difficult to recruit sane women to carry headless fetuses to their birth/death. It won’t be long, however, before these technical barriers are breached. The ethical barriers are already cracking. Lewis Wolpert, professor of biology at University College, London, finds producing headless humans “personally distasteful” but, given the shortage of organs, does not think distaste is sufficient reason not to go ahead with something that would save lives. And Professor Silver not only sees “nothing wrong, philosophically or rationally,” with producing headless humans for organ harvesting; he wants to convince a skeptical public that it is perfectly O.K. When prominent scientists are prepared to acquiesce in–or indeed encourage–the deliberate creation of deformed and dying quasi-human life, you know we are facing a bioethical abyss. Human beings are ends, not means. There is no grosser corruption of biotechnology than creating a human mutant and disemboweling it at our pleasure for spare parts.

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